Trauma – PTSD

Question:

Wow.   A society that made Cigarettes legal.  A society that sticks caffeine in every known drink to man.   A society who consumes so much caffeine each day.  Which is a stimulant of the brain, which does cause withdrawl.   Uh, so that means it’s an addiction an upper.   The would make 3/4 of North America losers.  The fact is we as a world are addicted one way or another…  some, yes some of us are truly at one with the world and themselves.   Very few. But what is truly happyness?  Working 40+ hours a week, trying to make as much money as you can?  Shopping at Gap?  Buying a nice house, living in a nice neighbourhood?  Having a beer, watching the game?  Sex with the wife/girlfriend?  Having children? Smoking weed, while listening to pink floyd?  Or taking cocaine so you can work more hours at work, because you hope to get that raise.  Besides most people who can afford cocaine are the people who make this stuff illegal.   The same law makers that make weed illegal are the same people sucking on a joint while their secretary is sucking their dick. Some how as we age, we loose the grasp at looking at the two sides. Now using marijuana, cocaine, valium and such  is not the answer to happyness.  It just masks the truth for short periods of time.  There you are right.   But to give up on people who make mistakes, then we would simply have to pass up everyone. Boy now only if we could have a drug that makes people social… oh wait.. alcohol.  dang..  I wanted to invent that one. I dunno its just my opinion. Take it easy. – Hide quoted text — Show quoted text – benzo’s are happiness pills just like pot and cocaine. if happiness could be created via chemicals, valium or pot would not have been so thoroughly discredited. life is brutally hard, and weak people will always grab for these pretend solutions. drug addicts are losers and should allowed to overdose. they want to die. let them. psychiatrists are evil.

Response:

- Hide quoted text — Show quoted text – Please,if you are going to post information, at least get the latest facts on the board. Julie I think you’ve misunderstood what Rand is all about, Julie. His campaign isn’t about presenting useful information. Its scaring folk off using benzodiazepines. At least that is one of his aims. He also has this thing about antidepressants and beta blockers. Considers them to be addictive too, and no doubt the work of the devil. In a Rand world the only anxiety/panic treatment would be Buspar and Scientology based mind control claptrap that is guaranteed to remove all emotion. Or so its author claims!!! Ian

Oh God….. I see Ms Ashtons best friend is back. Good Gawd!!!! Rand….. Go back where you came from. You know you are not welcome here. Some people never learn… Stephanie

Response:

– Hide quoted text — Show quoted text – Wow.   A society that made Cigarettes legal.  A society that sticks caffeine in every known drink to man.   A society who consumes so much caffeine each day.  Which is a stimulant of the brain, which does cause withdrawl.   Uh, so that means it’s an addiction an upper.   The would make 3/4 of North America losers.  The fact is we as a world are addicted one way or another…  some, yes some of us are truly at one with the world and themselves.   Very few. But what is truly happyness?  Working 40+ hours a week, trying to make as much money as you can?  Shopping at Gap?  Buying a nice house, living in a nice neighbourhood?  Having a beer, watching the game?  Sex with the wife/girlfriend?  Having children? Smoking weed, while listening to pink floyd?  Or taking cocaine so you can work more hours at work, because you hope to get that raise.  Besides most people who can afford cocaine are the people who make this stuff illegal.   The same law makers that make weed illegal are the same people sucking on a joint while their secretary is sucking their dick. Some how as we age, we loose the grasp at looking at the two sides. Now using marijuana, cocaine, valium and such  is not the answer to happyness.  It just masks the truth for short periods of time.  There you are right.   But to give up on people who make mistakes, then we would simply have to pass up everyone. Boy now only if we could have a drug that makes people social… oh wait.. alcohol.  dang..  I wanted to invent that one. I dunno its just my opinion. Take it easy. benzo’s are happiness pills just like pot and cocaine. if happiness could be created via chemicals, valium or pot would not have been so thoroughly discredited. life is brutally hard, and weak people will always grab for these pretend solutions. drug addicts are losers and should allowed to overdose. they want to die. let them. psychiatrists are evil.

if i catch you consuming pot, i’ll beat you with in an inch of your hippie life, freak-boy. Before you buy.

Response:

YOU DRUG ADDICTED AND CRAZY, DA? HOW LONG YOUR MIND THE SHIT?

– Hide quoted text — Show quoted text – I don’t usually bother reading any of the garbage you write, but I felt a need tonight to just say "Why don’t you buzz off, jerk-off."  You obviously have an agenda that you’re trying to push, but it has no place in this newsgroup. This newsgroup is for honest, everyday people with problems that are looking for help, support, or want to furnish guidance to others.  That’s certainly not you, so, as I say, "Cool it, asshole."  There are plenty of hate groups on the net that probably would welcome your drivel.

Response:

Verbal assault is illegal in many states and countries.  Your abuse and harassment is not mere trolling or personal expression.  It is not protected by the first amendment.  You could be taken to court on civil or criminal charges if someone sees fit to do so. Your behaviour is acceptable nowhere. –George "He paid no attention to the rumors, which he should have listened to…" Keiko Sofia Before you buy.

Response:

WHERE YOU FROM? I KNOW TARAS LITVINCHUK IN KYIV, YOU KNOW HIM? Ricky:     I don’t think that SSRIHater will answer your question because this is one obviously messed up individual.  S/he needs help

HE THE HE… HAVE THE "HUJ" BETWEEN THE LEGS. WHY YOU PROZAKIANS IMPOTENT LIKE ELIZABETH SHAPERE’S BOY FRIEND, PAUL ANTHONY GOWDER, JR., ESQ. ? dealing with the overwhelming compulsion to search for negative information about SSRIs

EASY "SEARCH"… ONLY KIND OF INFO ABOUT SSRIs anyway.. THERE IS GOOD INFO. ABOUT SSRIs? THAT NOT DRUG COMPANY FUNDED!?!? I NOT SEE ANY… and trolling alt.support newsgroups.  What kind of thrill can a person get out of making inflammatory posts towards people (1) with mental disorders

THEY CRAZY, GOOD FOR THE SHIT AND THEY HURT NORMAL, HUMAN PEOPLE… WE KNOW WHAT TO DO WITH CRAZY PROZAKIANS AND THE OTHER DRUG ADDICTS IN UKRAINE…..  and (2) that s/he doesn’t even know personally?

THEY MOSTLY PRETTY MUCH THE SAME… THE PROZAKIANS … DRUG INDUCED BEHAVIOR… IT’S WHY THEY PRETTY MUCH THE SAME… LIKE ALCOHOLICS ARE PRETTY MUCH THE SAME…  A very special kind of person … someone who is immature, who has never learned the social rules of politeness,

I AM MUCH MORE KULTURED THEN YOU…. A PROZAKIAN DRUG ADDICT SCUMBAG… I HAVE OBSERVED THE ACTING OUT BY YOU PROZAKIANS… CENSORSHIP, ISP PLUG PULLING RALLIES, ETC.. YOU ALL THE SHIT. I WISH YOU WERE IN UKRAINE RIGHT NOW…. and who has never developed compassion toward his/her fellow human beings.

YOU PROZAKIAN RAMPAGING, CHILD ABUSING, PET KILLING SHIT HAVE COMPASSION FOR US HUMANS? " P’TFU !" IN YOUR BORG ADDICT FACE! I SEE HOW YOUR KIND PUSH DRUGZ ON THE PREGNANT WOMEN… PUSHES DRUGZ ON NORMAL PEOPLE SO THAT THEY BE THE HEAD UP THE "SRAKA" LIKE YOU! THE NEWSPAPERS ARE FULL OF WHAT YOU PROZAKIANS DO… NOT ENOUGH HU-MAN CHILDREN KILLED FOR YOU? WHY IS IT THAT YOU PROZAKIANS NEVER KILL YOUR OWN KIND, ONLY HUMANS? – Hide quoted text — Show quoted text – Sounds like a "sociopath". We definitely need a NG called  alt.support.sociopath There are tons of folks on the Internet who belong there. Of course, by definition, they wouldn’t "support" each other very much. — Steven D. Litvintchouk Disclaimer:  As far as I am aware, the opinions expressed herein are not those of my employer.

Response:

Do you think her liberal loser b/f would make her swallow all her pillz and then defecate in her mouth to help her swallow them?  I do.  =) What else is the bitch good for? I love fucking with E — headcases are such an easy touch.  =) V benzo’s are happiness pills just like pot and cocaine. if happiness could be created via chemicals, valium or pot would not have been so thoroughly discredited. life is brutally hard, and weak people will always grab for these pretend solutions. drug addicts are losers and should allowed to overdose. they want to die. let them. psychiatrists are evil.   "flight ofthe phoenix"

– Hide quoted text — Show quoted text – Rapaport M, Braff DL. Alprazolam and Hostility. American Journal of Psychiatry 1985; 142: 146. " Monoamine oxidase inhibitors suppress the REM sleep and are correlated with patient self-reports of decreased dreaming. Recently we treated a patient who said she began having violent sadomasochistic nightmares and the return of self-mutilatory impulses after 0.25 mg t.i.d. of alprazolam was added to her regimen of tranylcypromine, 30 mg/day. Both the patients sadomasochistic nightmares and her self-mutilatory impulses ceased 24 hours after her last dose of alprazolam." [Key words; Xanax, alprazolam, nightmares] Regestein QR, Reich P. Agitation Observed During Treatment with Newer Hypnotic Drugs. Journal of Clinical Psychiatry 1985; 46: 280-283. Side effects involving agitation, e.g. sleepwalking, anger, and panic, were observed in 10 insomniac patients treated with temazepam or triazolam but not other benzodiazepines. Each patient described these side effects as uncharacteristic. Milder agitation was observed in 2 cases. In 4 cases, these effects were doubted by the precribing physician. This type of side effect has been only slowly recognised for other benzodiazepines and has not been much reported for these newer agents. Agitation observed during treatment with these agents may be related to their short elimination half-lives. [SUMMARY p. 280] [Key words; Halcion, Euhypnos, Normison, triazolam, temazepam, anxiety, aggression, hostility, paradoxical effects] Rejent TA, Wahl KC. Diazepam Abuse: Incidence, Rapid Screening and Confirming Methods. Clinical Chemistry 1976; 22: 889-891. " The abuse of drugs continues unabated in the United States. Awareness of "hard drug" use predominates in the news media and funded programs, but the facts concerning other drug misuse are generally hidden. Diazepam (and probably others) are heavily misused, but are not the subject of critical editorialization." " Highly prescribed psychotropic drugs can easily end up in the hands of many others. Therefore, the clinical analyst should be aware of drug popularity, which in our present society leads to overuse, abuse, and often requires medical intervention in a clinical emergency . " [p. 891] [Key words; addiction, abuse, dependence] Rementeria JL, Bhat K. Withdrawal Symptoms in Neonates From Intrauterine Exposure to Diazepam. Journal of Pediatrics 1977; 90: 123-126. Three infants are presented who had withdrawal symptoms after prolonged, intrauterine exposure to diazepam. Symptoms, clinical course, management, and laboratory findings are described. Some physiologic aspects of diazepam in the fetus and neonate are discussed. One infant died at six weeks of age; death was attributed to the sudden infant death syndrome. [ABSTRACT p.123] [Key words; Valium, diazepam, dependence, withdrawal, infants, pregnancy] Rickels K, Case WG, Schweizer EE, Swenson C, Fridman RB. Low-Dose Dependence in Chronic Benzodiazepine Users: A Preliminary Report on 119 Patients. Psychopharmacology Bulletin 1986; 22: 407-415. " In fact, one hard-earned lesson is that long-term BZ users are in need of much more intensive psychiatric and social support than other anxious or depressed patients. " [p. 414] [Key words; long-term effects] Rickels K, Schweizer E, Case G, Greenblatt DJ. Long-Term Therapeutic Use of Benzodiazepines. I. Effects of Abrupt Discontinuation. Archives of General Psychiatry 1990; 47: 899-907. " Patients who were able to remain free of benzodiazepines for at least 5 weeks obtained lower levels of anxiety than before benzodiazepine discontinuation. " [p. 899] [Key words; long-term effects, detoxification] Rigby J, Harvey M, Davies DR. Mania Precipitated by Benzodiazepine Withdrawal. Acta Psychiatrica Scandinavica 1989; 79: 406-407. A case of mania following abrupt benzodiazepine withdrawal in an 83-year-old woman is described. It is argued that the withdrawal state acted as a significant life event in precipitating the manic episode. [ABSTRACT p. 406] [Key words; Ativan, lorazepam, addiction, dependence, withdrawal, mania] Risse SC, Whitters A, Burke J, Chen S, Scurfield RM, Raskind MA. Severe Withdrawal Symptoms after Discontinuation of Alprazolam in Eight Patients with Combat-Induced Posttraumatic Stress Disorder. Journal of Clinical Psychiatry 1990; 51: 206-209. Eight patients with combat-induced posttraumatic stress disorder (PTSD) receiving long-term alprazolam therapy for anxiety or depression (maximum dose of 2-9 mg/day for 1-5 years) had alprazolam therapy withdrawn. Most of the patients underwent gradual medication withdrawal. All patients had a prior history of alcohol abuse or benzodiazepine dependence. During withdrawal, all patients had severe reactions including anxiety, sleep disturbance, rage reactions, hyperalertness, increased nightmares, and intrusive thoughts; and 6 of the 8 patient s had homicidal ideation. As a result of this report, the authors suggest that the potential for severe withdrawal reactions, even with gradual tapering, should be considered before prescribing alprazolam therapy for this group of patients. [ABSTRACT p. 206] [Key words; Xanax, alprazolam, addiction, dependence, withdrawal, detoxification, hostility, aggression, nightmares, insomnia] Rivas F, Hernandez A, Cantu JM. Acentric Craniofacial Cleft in a Newborn Female Prenatally Exposed to a High Dose of Diazepam. Teratology 1984; 30: 179-180. A newborn female with craniofacial clefts, including cleft lip and palate, was studied. The mother had ingested 580 mg of diazepam in a single dose at about the 43rd day of gestation. The synchronism of drug intake and the embryological development of the affected structures suggests an etiopathogenic relationship. [ABSTRACT p. 179] [Key words; teratogenic effects, infants] Roberts K, Vass N. Schneiderian First-Rank Symptoms Caused by Benzodiazepine Withdrawal. British Journal of Psychiatry 1986; 148: 593-594. Benzodiazepine withdrawal has been found to give rise to numerous physical and psychological symptoms. This paper describes, for the first time, Schneiderian first-rank symptoms of schizophrenia caused by such withdrawal. [SUMMARY p. 593] [Key words; addiction, withdrawal, abuse, dependence, withdrawal psychosis] Roche Products Inc. Manati, Puerto Rico. " The effectiveness of Valium in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. " [p.893] [ In advertisement for "Valium", Archives of General Psychiatry 1990; 47: 893.] " SIDE EFFECTS: Drowsiness, confusion, diplopia, hypotension, changes in libido, nausea, fatigue, depression, dysarthria, jaundice, skin rash, ataxia, constipation, headache, incontinence, changes in salivation, slurred speech, tremor, vertigo, urinary retention, blurred vision. Paradoxical reactions such as acute hyperexcited states, anxiety, hallucinations, increased muscle spasticity, insomnia, rage, sleep disturbances, stimulation have been reported; should these occur, discontinue drug. " Romney DM, Angus WR. A Brief Review of the Effects of Diazepam on Memory. Psychopharmacology Bulletin 1984; 20: 313-316. " Moreover, it [i.e. diazepam] appears to produce side effects, previously unnoticed, both on mood, causing depression and rage, and on cognitive and psychomotor functioning. " [p. 313] [Key words; Valium, diazepam, depression, aggression, cognitive impairment, psychomotor impairment] Ross M. Lorazepam-Associated Drug Dependence. Journal of the Royal College of General Practioners 1986; February: 86. " I should like to draw attention to what, in my opinion, are the unequivocal risks of lorazepam-associated drug dependence and exaggerated withdrawal symptoms. In

… read more »

Response:

benzo’s are happiness pills just like pot and cocaine. if happiness could be created via chemicals, valium or pot would not have been so thoroughly discredited. life is brutally hard, and weak people will always grab for these pretend solutions. drug addicts are losers and should allowed to overdose. they want to die. let them. psychiatrists are evil. – Hide quoted text — Show quoted text – Rapaport M, Braff DL. Alprazolam and Hostility. American Journal of Psychiatry 1985; 142: 146. " Monoamine oxidase inhibitors suppress the REM sleep and are correlated with patient self-reports of decreased dreaming. Recently we treated a patient who said she began having violent sadomasochistic nightmares and the return of self-mutilatory impulses after 0.25 mg t.i.d. of alprazolam was added to her regimen of tranylcypromine, 30 mg/day. Both the patients sadomasochistic nightmares and her self-mutilatory impulses ceased 24 hours after her last dose of alprazolam." [Key words; Xanax, alprazolam, nightmares] Regestein QR, Reich P. Agitation Observed During Treatment with Newer Hypnotic Drugs. Journal of Clinical Psychiatry 1985; 46: 280-283. Side effects involving agitation, e.g. sleepwalking, anger, and panic, were observed in 10 insomniac patients treated with temazepam or triazolam but not other benzodiazepines. Each patient described these side effects as uncharacteristic. Milder agitation was observed in 2 cases. In 4 cases, these effects were doubted by the precribing physician. This type of side effect has been only slowly recognised for other benzodiazepines and has not been much reported for these newer agents. Agitation observed during treatment with these agents may be related to their short elimination half-lives. [SUMMARY p. 280] [Key words; Halcion, Euhypnos, Normison, triazolam, temazepam, anxiety, aggression, hostility, paradoxical effects] Rejent TA, Wahl KC. Diazepam Abuse: Incidence, Rapid Screening and Confirming Methods. Clinical Chemistry 1976; 22: 889-891. " The abuse of drugs continues unabated in the United States. Awareness of "hard drug" use predominates in the news media and funded programs, but the facts concerning other drug misuse are generally hidden. Diazepam (and probably others) are heavily misused, but are not the subject of critical editorialization." " Highly prescribed psychotropic drugs can easily end up in the hands of many others. Therefore, the clinical analyst should be aware of drug popularity, which in our present society leads to overuse, abuse, and often requires medical intervention in a clinical emergency . " [p. 891] [Key words; addiction, abuse, dependence] Rementeria JL, Bhat K. Withdrawal Symptoms in Neonates From Intrauterine Exposure to Diazepam. Journal of Pediatrics 1977; 90: 123-126. Three infants are presented who had withdrawal symptoms after prolonged, intrauterine exposure to diazepam. Symptoms, clinical course, management, and laboratory findings are described. Some physiologic aspects of diazepam in the fetus and neonate are discussed. One infant died at six weeks of age; death was attributed to the sudden infant death syndrome. [ABSTRACT p.123] [Key words; Valium, diazepam, dependence, withdrawal, infants, pregnancy] Rickels K, Case WG, Schweizer EE, Swenson C, Fridman RB. Low-Dose Dependence in Chronic Benzodiazepine Users: A Preliminary Report on 119 Patients. Psychopharmacology Bulletin 1986; 22: 407-415. " In fact, one hard-earned lesson is that long-term BZ users are in need of much more intensive psychiatric and social support than other anxious or depressed patients. " [p. 414] [Key words; long-term effects] Rickels K, Schweizer E, Case G, Greenblatt DJ. Long-Term Therapeutic Use of Benzodiazepines. I. Effects of Abrupt Discontinuation. Archives of General Psychiatry 1990; 47: 899-907. " Patients who were able to remain free of benzodiazepines for at least 5 weeks obtained lower levels of anxiety than before benzodiazepine discontinuation. " [p. 899] [Key words; long-term effects, detoxification] Rigby J, Harvey M, Davies DR. Mania Precipitated by Benzodiazepine Withdrawal. Acta Psychiatrica Scandinavica 1989; 79: 406-407. A case of mania following abrupt benzodiazepine withdrawal in an 83-year-old woman is described. It is argued that the withdrawal state acted as a significant life event in precipitating the manic episode. [ABSTRACT p. 406] [Key words; Ativan, lorazepam, addiction, dependence, withdrawal, mania] Risse SC, Whitters A, Burke J, Chen S, Scurfield RM, Raskind MA. Severe Withdrawal Symptoms after Discontinuation of Alprazolam in Eight Patients with Combat-Induced Posttraumatic Stress Disorder. Journal of Clinical Psychiatry 1990; 51: 206-209. Eight patients with combat-induced posttraumatic stress disorder (PTSD) receiving long-term alprazolam therapy for anxiety or depression (maximum dose of 2-9 mg/day for 1-5 years) had alprazolam therapy withdrawn. Most of the patients underwent gradual medication withdrawal. All patients had a prior history of alcohol abuse or benzodiazepine dependence. During withdrawal, all patients had severe reactions including anxiety, sleep disturbance, rage reactions, hyperalertness, increased nightmares, and intrusive thoughts; and 6 of the 8 patient s had homicidal ideation. As a result of this report, the authors suggest that the potential for severe withdrawal reactions, even with gradual tapering, should be considered before prescribing alprazolam therapy for this group of patients. [ABSTRACT p. 206] [Key words; Xanax, alprazolam, addiction, dependence, withdrawal, detoxification, hostility, aggression, nightmares, insomnia] Rivas F, Hernandez A, Cantu JM. Acentric Craniofacial Cleft in a Newborn Female Prenatally Exposed to a High Dose of Diazepam. Teratology 1984; 30: 179-180. A newborn female with craniofacial clefts, including cleft lip and palate, was studied. The mother had ingested 580 mg of diazepam in a single dose at about the 43rd day of gestation. The synchronism of drug intake and the embryological development of the affected structures suggests an etiopathogenic relationship. [ABSTRACT p. 179] [Key words; teratogenic effects, infants] Roberts K, Vass N. Schneiderian First-Rank Symptoms Caused by Benzodiazepine Withdrawal. British Journal of Psychiatry 1986; 148: 593-594. Benzodiazepine withdrawal has been found to give rise to numerous physical and psychological symptoms. This paper describes, for the first time, Schneiderian first-rank symptoms of schizophrenia caused by such withdrawal. [SUMMARY p. 593] [Key words; addiction, withdrawal, abuse, dependence, withdrawal psychosis] Roche Products Inc. Manati, Puerto Rico. " The effectiveness of Valium in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. " [p.893] [ In advertisement for "Valium", Archives of General Psychiatry 1990; 47: 893.] " SIDE EFFECTS: Drowsiness, confusion, diplopia, hypotension, changes in libido, nausea, fatigue, depression, dysarthria, jaundice, skin rash, ataxia, constipation, headache, incontinence, changes in salivation, slurred speech, tremor, vertigo, urinary retention, blurred vision. Paradoxical reactions such as acute hyperexcited states, anxiety, hallucinations, increased muscle spasticity, insomnia, rage, sleep disturbances, stimulation have been reported; should these occur, discontinue drug. " Romney DM, Angus WR. A Brief Review of the Effects of Diazepam on Memory. Psychopharmacology Bulletin 1984; 20: 313-316. " Moreover, it [i.e. diazepam] appears to produce side effects, previously unnoticed, both on mood, causing depression and rage, and on cognitive and psychomotor functioning. " [p. 313] [Key words; Valium, diazepam, depression, aggression, cognitive impairment, psychomotor impairment] Ross M. Lorazepam-Associated Drug Dependence. Journal of the Royal College of General Practioners 1986; February: 86. " I should like to draw attention to what, in my opinion, are the unequivocal risks of lorazepam-associated drug dependence and exaggerated withdrawal symptoms. In my experience, this can occur often with low dosage, short courses and for many months after cessation of therapy. It is common to find other general practioners and psychiatrists who share this view and there is also widespread lay awareness of the problem. For the last year and a half I have been communicating with the Committee on Safety of Medicines about the problem. They answer that they have received few yellow card reports on this problem. My personal view is that this is because doctors do not realise that reporting an expected side-effect of a drug is as useful for epidemiological purposes as is reporting an unexpected side-effect for general scientific purposes. I should like, therefore, to appeal to all the general practitioners who must be seeing this problem, to

… read more »

Response:

Please,if you are going to post information, at least get the latest facts on the board. Julie

I think you’ve misunderstood what Rand is all about, Julie. His campaign isn’t about presenting useful information. Its scaring folk off using benzodiazepines. At least that is one of his aims. He also has this thing about antidepressants and beta blockers. Considers them to be addictive too, and no doubt the work of the devil. In a Rand world the only anxiety/panic treatment would be Buspar and Scientology based mind control claptrap that is guaranteed to remove all emotion. Or so its author claims!!! Ian

Response:

Ricky:     I don’t think that SSRIHater will answer your question because this is one obviously messed up individual.  S/he needs help dealing with the overwhelming compulsion to search for negative information about SSRIs and trolling alt.support newsgroups.  What kind of thrill can a person get out of making inflammatory posts towards people (1) with mental disorders and (2) that s/he doesn’t even know personally?  A very special kind of person … someone who is immature, who has never learned the social rules of politeness, and who has never developed compassion toward his/her fellow human beings.  

Sounds like a "sociopath". We definitely need a NG called  alt.support.sociopath There are tons of folks on the Internet who belong there. Of course, by definition, they wouldn’t "support" each other very much. — Steven D. Litvintchouk                   Disclaimer:  As far as I am aware, the opinions expressed herein             are not those of my employer.

Response:

Ricky:     I don’t think that SSRIHater will answer your question because this is one obviously messed up individual.  S/he needs help dealing with the overwhelming compulsion to search for negative information about SSRIs and trolling alt.support newsgroups.  What kind of thrill can a person get out of making inflammatory posts towards people (1) with mental disorders and (2) that s/he doesn’t even know personally?  A very special kind of person … someone who is immature, who has never learned the social rules of politeness, and who has never developed compassion toward his/her fellow human beings.  I’d suggest long-term therapy to overcome these debilitating problems … it’s kind of sad really.     Lachryma

Response:

Ricky:     I don’t think that SSRIHater will answer your question because this is one obviously messed up individual.  S/he needs help dealing with the overwhelming compulsion to search for negative information about SSRIs and trolling alt.support newsgroups.  What kind of thrill can a person get out of making inflammatory posts towards people (1) with mental disorders and (2) that s/he doesn’t even know personally?  A very special kind of person … someone who is immature, who has never learned the social rules of politeness, and who has never developed compassion toward his/her fellow human beings.  I’d suggest long-term therapy to overcome these debilitating problems … it’s kind of sad really.     Lachryma

SSRI Drugz too? What kind of drugz you eat? How much? How many years? You still crazy? Crazier yes? Pills no work? Please to report to Ukrainian Isolation Camps for Borg. Guard will escort you. First you put on this 5 point restraint jacket. You sick in mind.

Response:

Please,if you are going to post information, at least get the latest facts on the board. Julie

To add, he also posted about the med "Halcion" which is not a med for anxiety disorders and is banned in many countries…..what was the purpose of posting Jackie

Response:

– Hide quoted text — Show quoted text – Rapaport M, Braff DL. Alprazolam and Hostility. American Journal of Psychiatry 1985; 142: 146. " Monoamine oxidase inhibitors suppress the REM sleep and are correlated with patient self-reports of decreased dreaming. Recently we treated a patient who said she began having violent sadomasochistic nightmares and the return of self-mutilatory impulses after 0.25 mg t.i.d. of alprazolam was added to her regimen of tranylcypromine, 30 mg/day. Both the patients sadomasochistic nightmares and her self-mutilatory impulses ceased 24 hours after her last dose of alprazolam." [Key words; Xanax, alprazolam, nightmares] Regestein QR, Reich P. Agitation Observed During Treatment with Newer Hypnotic Drugs. Journal of Clinical Psychiatry 1985; 46: 280-283. Side effects involving agitation, e.g. sleepwalking, anger, and panic, were observed in 10 insomniac patients treated with temazepam or triazolam but not other benzodiazepines. Each patient described these side effects as uncharacteristic. Milder agitation was observed in 2 cases. In 4 cases, these effects were doubted by the precribing physician. This type of side effect has been only slowly recognised for other benzodiazepines and has not been much reported for these newer agents. Agitation observed during treatment with these agents may be related to their short elimination half-lives. [SUMMARY p. 280] [Key words; Halcion, Euhypnos, Normison, triazolam, temazepam, anxiety, aggression, hostility, paradoxical effects] Rejent TA, Wahl KC. Diazepam Abuse: Incidence, Rapid Screening and Confirming Methods. Clinical Chemistry 1976; 22: 889-891. " The abuse of drugs continues unabated in the United States. Awareness of "hard drug" use predominates in the news media and funded programs, but the facts concerning other drug misuse are generally hidden. Diazepam (and probably others) are heavily misused, but are not the subject of critical editorialization." " Highly prescribed psychotropic drugs can easily end up in the hands of many others. Therefore, the clinical analyst should be aware of drug popularity, which in our present society leads to overuse, abuse, and often requires medical intervention in a clinical emergency . " [p. 891] [Key words; addiction, abuse, dependence] Rementeria JL, Bhat K. Withdrawal Symptoms in Neonates From Intrauterine Exposure to Diazepam. Journal of Pediatrics 1977; 90: 123-126. Three infants are presented who had withdrawal symptoms after prolonged, intrauterine exposure to diazepam. Symptoms, clinical course, management, and laboratory findings are described. Some physiologic aspects of diazepam in the fetus and neonate are discussed. One infant died at six weeks of age; death was attributed to the sudden infant death syndrome. [ABSTRACT p.123] [Key words; Valium, diazepam, dependence, withdrawal, infants, pregnancy] Rickels K, Case WG, Schweizer EE, Swenson C, Fridman RB. Low-Dose Dependence in Chronic Benzodiazepine Users: A Preliminary Report on 119 Patients. Psychopharmacology Bulletin 1986; 22: 407-415. " In fact, one hard-earned lesson is that long-term BZ users are in need of much more intensive psychiatric and social support than other anxious or depressed patients. " [p. 414] [Key words; long-term effects] Rickels K, Schweizer E, Case G, Greenblatt DJ. Long-Term Therapeutic Use of Benzodiazepines. I. Effects of Abrupt Discontinuation. Archives of General Psychiatry 1990; 47: 899-907. " Patients who were able to remain free of benzodiazepines for at least 5 weeks obtained lower levels of anxiety than before benzodiazepine discontinuation. " [p. 899] [Key words; long-term effects, detoxification] Rigby J, Harvey M, Davies DR. Mania Precipitated by Benzodiazepine Withdrawal. Acta Psychiatrica Scandinavica 1989; 79: 406-407. A case of mania following abrupt benzodiazepine withdrawal in an 83-year-old woman is described. It is argued that the withdrawal state acted as a significant life event in precipitating the manic episode. [ABSTRACT p. 406] [Key words; Ativan, lorazepam, addiction, dependence, withdrawal, mania] Risse SC, Whitters A, Burke J, Chen S, Scurfield RM, Raskind MA. Severe Withdrawal Symptoms after Discontinuation of Alprazolam in Eight Patients with Combat-Induced Posttraumatic Stress Disorder. Journal of Clinical Psychiatry 1990; 51: 206-209. Eight patients with combat-induced posttraumatic stress disorder (PTSD) receiving long-term alprazolam therapy for anxiety or depression (maximum dose of 2-9 mg/day for 1-5 years) had alprazolam therapy withdrawn. Most of the patients underwent gradual medication withdrawal. All patients had a prior history of alcohol abuse or benzodiazepine dependence. During withdrawal, all patients had severe reactions including anxiety, sleep disturbance, rage reactions, hyperalertness, increased nightmares, and intrusive thoughts; and 6 of the 8 patient s had homicidal ideation. As a result of this report, the authors suggest that the potential for severe withdrawal reactions, even with gradual tapering, should be considered before prescribing alprazolam therapy for this group of patients. [ABSTRACT p. 206] [Key words; Xanax, alprazolam, addiction, dependence, withdrawal, detoxification, hostility, aggression, nightmares, insomnia] Rivas F, Hernandez A, Cantu JM. Acentric Craniofacial Cleft in a Newborn Female Prenatally Exposed to a High Dose of Diazepam. Teratology 1984; 30: 179-180. A newborn female with craniofacial clefts, including cleft lip and palate, was studied. The mother had ingested 580 mg of diazepam in a single dose at about the 43rd day of gestation. The synchronism of drug intake and the embryological development of the affected structures suggests an etiopathogenic relationship. [ABSTRACT p. 179] [Key words; teratogenic effects, infants] Roberts K, Vass N. Schneiderian First-Rank Symptoms Caused by Benzodiazepine Withdrawal. British Journal of Psychiatry 1986; 148: 593-594. Benzodiazepine withdrawal has been found to give rise to numerous physical and psychological symptoms. This paper describes, for the first time, Schneiderian first-rank symptoms of schizophrenia caused by such withdrawal. [SUMMARY p. 593] [Key words; addiction, withdrawal, abuse, dependence, withdrawal psychosis] Roche Products Inc. Manati, Puerto Rico. " The effectiveness of Valium in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. " [p.893] [ In advertisement for "Valium", Archives of General Psychiatry 1990; 47: 893.] " SIDE EFFECTS: Drowsiness, confusion, diplopia, hypotension, changes in libido, nausea, fatigue, depression, dysarthria, jaundice, skin rash, ataxia, constipation, headache, incontinence, changes in salivation, slurred speech, tremor, vertigo, urinary retention, blurred vision. Paradoxical reactions such as acute hyperexcited states, anxiety, hallucinations, increased muscle spasticity, insomnia, rage, sleep disturbances, stimulation have been reported; should these occur, discontinue drug. " Romney DM, Angus WR. A Brief Review of the Effects of Diazepam on Memory. Psychopharmacology Bulletin 1984; 20: 313-316. " Moreover, it [i.e. diazepam] appears to produce side effects, previously unnoticed, both on mood, causing depression and rage, and on cognitive and psychomotor functioning. " [p. 313] [Key words; Valium, diazepam, depression, aggression, cognitive impairment, psychomotor impairment] Ross M. Lorazepam-Associated Drug Dependence. Journal of the Royal College of General Practioners 1986; February: 86. " I should like to draw attention to what, in my opinion, are the unequivocal risks of lorazepam-associated drug dependence and exaggerated withdrawal symptoms. In my experience, this can occur often with low dosage, short courses and for many months after cessation of therapy. It is common to find other general practioners and psychiatrists who share this view and there is also widespread lay awareness of the problem. For the last year and a half I have been communicating with the Committee on Safety of Medicines about the problem. They answer that they have received few yellow card reports on this problem. My personal view is that this is because doctors do not realise that reporting an expected side-effect of a drug is as useful for epidemiological purposes as is reporting an unexpected side-effect for general scientific purposes. I should like, therefore, to appeal to all the general practitioners who must be seeing this problem, to report any cases to the Committee on Safety of Medicines. " [p. 86] [Key words; Ativan, lorazepam, addiction, dependence, abuse, withdrawal] Rosenbaum JF, SW Woods, Groves JE, Klerman GL. Emergence of Hostility During Alprazolam Treatment. American Journal of Psychiatry 1984; 141: 792-793. Of 80 patients given alprazolam, eight became hostile early in treatment. The authors suggest that alprazolam-induced hostility may be more likely in patients with well-suppressed chronic anger and resentment and cite reports of hostility associated with other benzodiazepines. [SUMMARY p. 792] [Key words; Xanax, alprazolam, aggression, paradoxical effects] Rowlatt RJ. Effects of Maternal Diazepam. BMJ 1978; 1: 985. " High doses (30 mg or more) of diazepam administered during labour cause, in the infant, failure to start breathing, shallow, inadequate respirations, periodic cessations of respiration, floppiness, subnormal

… read more »

Response:

Answer the question SSRI. What’s up with you and your hate towards SSRi’s. – Hide quoted text — Show quoted text – Rapaport M, Braff DL. Alprazolam and Hostility. American Journal of Psychiatry 1985; 142: 146. " Monoamine oxidase inhibitors suppress the REM sleep and are correlated with patient self-reports of decreased dreaming. Recently we treated a patient who said she began having violent sadomasochistic nightmares and the return of self-mutilatory impulses after 0.25 mg t.i.d. of alprazolam was added to her regimen of tranylcypromine, 30 mg/day. Both the patients sadomasochistic nightmares and her self-mutilatory impulses ceased 24 hours after her last dose of alprazolam." [Key words; Xanax, alprazolam, nightmares] Regestein QR, Reich P. Agitation Observed During Treatment with Newer Hypnotic Drugs. Journal of Clinical Psychiatry 1985; 46: 280-283. Side effects involving agitation, e.g. sleepwalking, anger, and panic, were observed in 10 insomniac patients treated with temazepam or triazolam but not other benzodiazepines. Each patient described these side effects as uncharacteristic. Milder agitation was observed in 2 cases. In 4 cases, these effects were doubted by the precribing physician. This type of side effect has been only slowly recognised for other benzodiazepines and has not been much reported for these newer agents. Agitation observed during treatment with these agents may be related to their short elimination half-lives. [SUMMARY p. 280] [Key words; Halcion, Euhypnos, Normison, triazolam, temazepam, anxiety, aggression, hostility, paradoxical effects] Rejent TA, Wahl KC. Diazepam Abuse: Incidence, Rapid Screening and Confirming Methods. Clinical Chemistry 1976; 22: 889-891. " The abuse of drugs continues unabated in the United States. Awareness of "hard drug" use predominates in the news media and funded programs, but the facts concerning other drug misuse are generally hidden. Diazepam (and probably others) are heavily misused, but are not the subject of critical editorialization." " Highly prescribed psychotropic drugs can easily end up in the hands of many others. Therefore, the clinical analyst should be aware of drug popularity, which in our present society leads to overuse, abuse, and often requires medical intervention in a clinical emergency . " [p. 891] [Key words; addiction, abuse, dependence] Rementeria JL, Bhat K. Withdrawal Symptoms in Neonates From Intrauterine Exposure to Diazepam. Journal of Pediatrics 1977; 90: 123-126. Three infants are presented who had withdrawal symptoms after prolonged, intrauterine exposure to diazepam. Symptoms, clinical course, management, and laboratory findings are described. Some physiologic aspects of diazepam in the fetus and neonate are discussed. One infant died at six weeks of age; death was attributed to the sudden infant death syndrome. [ABSTRACT p.123] [Key words; Valium, diazepam, dependence, withdrawal, infants, pregnancy] Rickels K, Case WG, Schweizer EE, Swenson C, Fridman RB. Low-Dose Dependence in Chronic Benzodiazepine Users: A Preliminary Report on 119 Patients. Psychopharmacology Bulletin 1986; 22: 407-415. " In fact, one hard-earned lesson is that long-term BZ users are in need of much more intensive psychiatric and social support than other anxious or depressed patients. " [p. 414] [Key words; long-term effects] Rickels K, Schweizer E, Case G, Greenblatt DJ. Long-Term Therapeutic Use of Benzodiazepines. I. Effects of Abrupt Discontinuation. Archives of General Psychiatry 1990; 47: 899-907. " Patients who were able to remain free of benzodiazepines for at least 5 weeks obtained lower levels of anxiety than before benzodiazepine discontinuation. " [p. 899] [Key words; long-term effects, detoxification] Rigby J, Harvey M, Davies DR. Mania Precipitated by Benzodiazepine Withdrawal. Acta Psychiatrica Scandinavica 1989; 79: 406-407. A case of mania following abrupt benzodiazepine withdrawal in an 83-year-old woman is described. It is argued that the withdrawal state acted as a significant life event in precipitating the manic episode. [ABSTRACT p. 406] [Key words; Ativan, lorazepam, addiction, dependence, withdrawal, mania] Risse SC, Whitters A, Burke J, Chen S, Scurfield RM, Raskind MA. Severe Withdrawal Symptoms after Discontinuation of Alprazolam in Eight Patients with Combat-Induced Posttraumatic Stress Disorder. Journal of Clinical Psychiatry 1990; 51: 206-209. Eight patients with combat-induced posttraumatic stress disorder (PTSD) receiving long-term alprazolam therapy for anxiety or depression (maximum dose of 2-9 mg/day for 1-5 years) had alprazolam therapy withdrawn. Most of the patients underwent gradual medication withdrawal. All patients had a prior history of alcohol abuse or benzodiazepine dependence. During withdrawal, all patients had severe reactions including anxiety, sleep disturbance, rage reactions, hyperalertness, increased nightmares, and intrusive thoughts; and 6 of the 8 patient s had homicidal ideation. As a result of this report, the authors suggest that the potential for severe withdrawal reactions, even with gradual tapering, should be considered before prescribing alprazolam therapy for this group of patients. [ABSTRACT p. 206] [Key words; Xanax, alprazolam, addiction, dependence, withdrawal, detoxification, hostility, aggression, nightmares, insomnia] Rivas F, Hernandez A, Cantu JM. Acentric Craniofacial Cleft in a Newborn Female Prenatally Exposed to a High Dose of Diazepam. Teratology 1984; 30: 179-180. A newborn female with craniofacial clefts, including cleft lip and palate, was studied. The mother had ingested 580 mg of diazepam in a single dose at about the 43rd day of gestation. The synchronism of drug intake and the embryological development of the affected structures suggests an etiopathogenic relationship. [ABSTRACT p. 179] [Key words; teratogenic effects, infants] Roberts K, Vass N. Schneiderian First-Rank Symptoms Caused by Benzodiazepine Withdrawal. British Journal of Psychiatry 1986; 148: 593-594. Benzodiazepine withdrawal has been found to give rise to numerous physical and psychological symptoms. This paper describes, for the first time, Schneiderian first-rank symptoms of schizophrenia caused by such withdrawal. [SUMMARY p. 593] [Key words; addiction, withdrawal, abuse, dependence, withdrawal psychosis] Roche Products Inc. Manati, Puerto Rico. " The effectiveness of Valium in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. " [p.893] [ In advertisement for "Valium", Archives of General Psychiatry 1990; 47: 893.] " SIDE EFFECTS: Drowsiness, confusion, diplopia, hypotension, changes in libido, nausea, fatigue, depression, dysarthria, jaundice, skin rash, ataxia, constipation, headache, incontinence, changes in salivation, slurred speech, tremor, vertigo, urinary retention, blurred vision. Paradoxical reactions such as acute hyperexcited states, anxiety, hallucinations, increased muscle spasticity, insomnia, rage, sleep disturbances, stimulation have been reported; should these occur, discontinue drug. " Romney DM, Angus WR. A Brief Review of the Effects of Diazepam on Memory. Psychopharmacology Bulletin 1984; 20: 313-316. " Moreover, it [i.e. diazepam] appears to produce side effects, previously unnoticed, both on mood, causing depression and rage, and on cognitive and psychomotor functioning. " [p. 313] [Key words; Valium, diazepam, depression, aggression, cognitive impairment, psychomotor impairment] Ross M. Lorazepam-Associated Drug Dependence. Journal of the Royal College of General Practioners 1986; February: 86. " I should like to draw attention to what, in my opinion, are the unequivocal risks of lorazepam-associated drug dependence and exaggerated withdrawal symptoms. In my experience, this can occur often with low dosage, short courses and for many months after cessation of therapy. It is common to find other general practioners and psychiatrists who share this view and there is also widespread lay awareness of the problem. For the last year and a half I have been communicating with the Committee on Safety of Medicines about the problem. They answer that they have received few yellow card reports on this problem. My personal view is that this is because doctors do not realise that reporting an expected side-effect of a drug is as useful for epidemiological purposes as is reporting an unexpected side-effect for general scientific purposes. I should like, therefore, to appeal to all the general practitioners who must be seeing this problem, to report any cases to the Committee on Safety of Medicines. " [p. 86] [Key words; Ativan, lorazepam, addiction, dependence, abuse, withdrawal] Rosenbaum JF, SW Woods, Groves JE, Klerman GL. Emergence of Hostility During Alprazolam Treatment. American Journal of Psychiatry 1984; 141: 792-793. Of 80 patients given alprazolam, eight became hostile early in treatment. The authors suggest that alprazolam-induced hostility may be more likely in patients with well-suppressed chronic anger and

… read more »

Response:

Alprazolam and Hostility. American Journal of Psychiatry 1985; Agitation Observed During Treatment with Newer Hypnotic Drugs. Journal of Clinical Psychiatry 1985; Diazepam Abuse: Incidence, Rapid Screening and Confirming Methods. Clinical Chemistry 1976; 22: Withdrawal Symptoms in Neonates From Intrauterine Exposure to Diazepam. Journal of Pediatrics 1977; 90: . Low-Dose Dependence in Chronic Benzodiazepine Users: A Preliminary Report on 119 Patients. Psychopharmacology Bulletin 1986;

. Long-Term Therapeutic Use of Benzodiazepines. I. Effects of Abrupt Discontinuation. Archives of General Psychiatry 1990; Mania Precipitated by Benzodiazepine Withdrawal. Acta Psychiatrica Scandinavica 1989; A case of mania following abrupt benzodiazepine withdrawal in an 83- year-old woman is described.

 Journal of Clinical Psychiatry 1990; High Dose of Diazepam. Teratology 1984; 30: Roberts K, Vass N. Schneiderian First

Rank Symptoms Caused by Benzodiazepine Withdrawal. British Journal of Psychiatry 1986; [ In advertisement for "Valium", Archives of General Psychiatry 1990; A Brief Review of the Effects of Diazepam on Memory. Psychopharmacology Bulletin 1984;

 Ross M. Lorazepam-Associated Drug Dependence. Journal of the Royal College of General Practioners 1986; February:

86.  Emergence of Hostility During Alprazolam Treatment. American Journal of Psychiatry 1984; 141: 792-793. Rowlatt RJ.

 Effects of Maternal Diazepam. BMJ 1978; Increase in Suicidal Thoughts and Tendencies Association with Diazepam Therapy. JAMA 1968;

I took the time to highlight the dates of the articles. The latest article is dated 1990. It is ten years old and it is in the best interest of everyone here to find the newer information,perhaps from 1999 or 2000. I also include the case study age of one participant. An 83 year old woman. Please,if you are going to post information, at least get the latest facts on the board. Julie Before you buy.

Response:

Rapaport M, Braff DL. Alprazolam and Hostility. American Journal of Psychiatry 1985; 142: 146. " Monoamine oxidase inhibitors suppress the REM sleep and are correlated with patient self-reports of decreased dreaming. Recently we treated a patient who said she began having violent sadomasochistic nightmares and the return of self-mutilatory impulses after 0.25 mg t.i.d. of alprazolam was added to her regimen of tranylcypromine, 30 mg/day. Both the patients sadomasochistic nightmares and her self-mutilatory impulses ceased 24 hours after her last dose of alprazolam." [Key words; Xanax, alprazolam, nightmares] Regestein QR, Reich P. Agitation Observed During Treatment with Newer Hypnotic Drugs. Journal of Clinical Psychiatry 1985; 46: 280-283. Side effects involving agitation, e.g. sleepwalking, anger, and panic, were observed in 10 insomniac patients treated with temazepam or triazolam but not other benzodiazepines. Each patient described these side effects as uncharacteristic. Milder agitation was observed in 2 cases. In 4 cases, these effects were doubted by the precribing physician. This type of side effect has been only slowly recognised for other benzodiazepines and has not been much reported for these newer agents. Agitation observed during treatment with these agents may be related to their short elimination half-lives. [SUMMARY p. 280] [Key words; Halcion, Euhypnos, Normison, triazolam, temazepam, anxiety, aggression, hostility, paradoxical effects] Rejent TA, Wahl KC. Diazepam Abuse: Incidence, Rapid Screening and Confirming Methods. Clinical Chemistry 1976; 22: 889-891. " The abuse of drugs continues unabated in the United States. Awareness of "hard drug" use predominates in the news media and funded programs, but the facts concerning other drug misuse are generally hidden. Diazepam (and probably others) are heavily misused, but are not the subject of critical editorialization." " Highly prescribed psychotropic drugs can easily end up in the hands of many others. Therefore, the clinical analyst should be aware of drug popularity, which in our present society leads to overuse, abuse, and often requires medical intervention in a clinical emergency . " [p. 891] [Key words; addiction, abuse, dependence] Rementeria JL, Bhat K. Withdrawal Symptoms in Neonates From Intrauterine Exposure to Diazepam. Journal of Pediatrics 1977; 90: 123-126. Three infants are presented who had withdrawal symptoms after prolonged, intrauterine exposure to diazepam. Symptoms, clinical course, management, and laboratory findings are described. Some physiologic aspects of diazepam in the fetus and neonate are discussed. One infant died at six weeks of age; death was attributed to the sudden infant death syndrome. [ABSTRACT p.123] [Key words; Valium, diazepam, dependence, withdrawal, infants, pregnancy] Rickels K, Case WG, Schweizer EE, Swenson C, Fridman RB. Low-Dose Dependence in Chronic Benzodiazepine Users: A Preliminary Report on 119 Patients. Psychopharmacology Bulletin 1986; 22: 407-415. " In fact, one hard-earned lesson is that long-term BZ users are in need of much more intensive psychiatric and social support than other anxious or depressed patients. " [p. 414] [Key words; long-term effects] Rickels K, Schweizer E, Case G, Greenblatt DJ. Long-Term Therapeutic Use of Benzodiazepines. I. Effects of Abrupt Discontinuation. Archives of General Psychiatry 1990; 47: 899-907. " Patients who were able to remain free of benzodiazepines for at least 5 weeks obtained lower levels of anxiety than before benzodiazepine discontinuation. " [p. 899] [Key words; long-term effects, detoxification] Rigby J, Harvey M, Davies DR. Mania Precipitated by Benzodiazepine Withdrawal. Acta Psychiatrica Scandinavica 1989; 79: 406-407. A case of mania following abrupt benzodiazepine withdrawal in an 83-year-old woman is described. It is argued that the withdrawal state acted as a significant life event in precipitating the manic episode. [ABSTRACT p. 406] [Key words; Ativan, lorazepam, addiction, dependence, withdrawal, mania] Risse SC, Whitters A, Burke J, Chen S, Scurfield RM, Raskind MA. Severe Withdrawal Symptoms after Discontinuation of Alprazolam in Eight Patients with Combat-Induced Posttraumatic Stress Disorder. Journal of Clinical Psychiatry 1990; 51: 206-209. Eight patients with combat-induced posttraumatic stress disorder (PTSD) receiving long-term alprazolam therapy for anxiety or depression (maximum dose of 2-9 mg/day for 1-5 years) had alprazolam therapy withdrawn. Most of the patients underwent gradual medication withdrawal. All patients had a prior history of alcohol abuse or benzodiazepine dependence. During withdrawal, all patients had severe reactions including anxiety, sleep disturbance, rage reactions, hyperalertness, increased nightmares, and intrusive thoughts; and 6 of the 8 patient s had homicidal ideation. As a result of this report, the authors suggest that the potential for severe withdrawal reactions, even with gradual tapering, should be considered before prescribing alprazolam therapy for this group of patients. [ABSTRACT p. 206] [Key words; Xanax, alprazolam, addiction, dependence, withdrawal, detoxification, hostility, aggression, nightmares, insomnia] Rivas F, Hernandez A, Cantu JM. Acentric Craniofacial Cleft in a Newborn Female Prenatally Exposed to a High Dose of Diazepam. Teratology 1984; 30: 179-180. A newborn female with craniofacial clefts, including cleft lip and palate, was studied. The mother had ingested 580 mg of diazepam in a single dose at about the 43rd day of gestation. The synchronism of drug intake and the embryological development of the affected structures suggests an etiopathogenic relationship. [ABSTRACT p. 179] [Key words; teratogenic effects, infants] Roberts K, Vass N. Schneiderian First-Rank Symptoms Caused by Benzodiazepine Withdrawal. British Journal of Psychiatry 1986; 148: 593-594. Benzodiazepine withdrawal has been found to give rise to numerous physical and psychological symptoms. This paper describes, for the first time, Schneiderian first-rank symptoms of schizophrenia caused by such withdrawal. [SUMMARY p. 593] [Key words; addiction, withdrawal, abuse, dependence, withdrawal psychosis] Roche Products Inc. Manati, Puerto Rico. " The effectiveness of Valium in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. " [p.893] [ In advertisement for "Valium", Archives of General Psychiatry 1990; 47: 893.] " SIDE EFFECTS: Drowsiness, confusion, diplopia, hypotension, changes in libido, nausea, fatigue, depression, dysarthria, jaundice, skin rash, ataxia, constipation, headache, incontinence, changes in salivation, slurred speech, tremor, vertigo, urinary retention, blurred vision. Paradoxical reactions such as acute hyperexcited states, anxiety, hallucinations, increased muscle spasticity, insomnia, rage, sleep disturbances, stimulation have been reported; should these occur, discontinue drug. " Romney DM, Angus WR. A Brief Review of the Effects of Diazepam on Memory. Psychopharmacology Bulletin 1984; 20: 313-316. " Moreover, it [i.e. diazepam] appears to produce side effects, previously unnoticed, both on mood, causing depression and rage, and on cognitive and psychomotor functioning. " [p. 313] [Key words; Valium, diazepam, depression, aggression, cognitive impairment, psychomotor impairment] Ross M. Lorazepam-Associated Drug Dependence. Journal of the Royal College of General Practioners 1986; February: 86. " I should like to draw attention to what, in my opinion, are the unequivocal risks of lorazepam-associated drug dependence and exaggerated withdrawal symptoms. In my experience, this can occur often with low dosage, short courses and for many months after cessation of therapy. It is common to find other general practioners and psychiatrists who share this view and there is also widespread lay awareness of the problem. For the last year and a half I have been communicating with the Committee on Safety of Medicines about the problem. They answer that they have received few yellow card reports on this problem. My personal view is that this is because doctors do not realise that reporting an expected side-effect of a drug is as useful for epidemiological purposes as is reporting an unexpected side-effect for general scientific purposes. I should like, therefore, to appeal to all the general practitioners who must be seeing this problem, to report any cases to the Committee on Safety of Medicines. " [p. 86] [Key words; Ativan, lorazepam, addiction, dependence, abuse, withdrawal] Rosenbaum JF, SW Woods, Groves JE, Klerman GL. Emergence of Hostility During Alprazolam Treatment. American Journal of Psychiatry 1984; 141: 792-793. Of 80 patients given alprazolam, eight became hostile early in treatment. The authors suggest that alprazolam-induced hostility may be more likely in patients with well-suppressed chronic anger and resentment and cite reports of hostility associated with other benzodiazepines. [SUMMARY p. 792] [Key words; Xanax, alprazolam, aggression, paradoxical effects] Rowlatt RJ. Effects of Maternal Diazepam. BMJ 1978; 1: 985. " High doses (30 mg or more) of diazepam administered during labour cause, in the infant, failure to start breathing, shallow, inadequate respirations, periodic cessations of respiration, floppiness, subnormal temperature, and poor sucking. These effects last several days and significant plasma levels of diazepam and of its active metabolites persist for up to eight days. Diazepam accumulates in tissue of the fetus, and is metabolised and excreted slowly by the newborn baby. " " The depressant effects of pethidine and other drugs given during labour would be made worse by diazepam. " " Diazepam is excreted in breast milk, which may sedate the baby and cause feeding difficulty. Finally, there is the fear of impairing future intellectual development by exposing the … read more »

Response:

Related Posts