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NIGHTMARES&VIOLENT THOUGHTS??

Question:

Has anyone suffered from vivid nightmares, and thoughts of violence while on serzone?? Im on seroquel, depakote, and serzone(2 weeks on serzone).Any comments appreciated.

Response:

Not on Serzone, but that is one of the possible side effects of many medications.  I had disturbing nightmares when getting OFF of Paxil. Knowing what they are helps some, but maybe you should talk to your doctor about changing to something else, or adjusting the dosages of what you are taking.  Sometimes a very slight change is all it takes to get rid of unpleasant side effects. (and I would call that one UNpleasant) – Hide quoted text — Show quoted text – Has anyone suffered from vivid nightmares, and thoughts of violence while on serzone?? Im on seroquel, depakote, and serzone(2 weeks on serzone).Any comments appreciated.

Response:

Has anyone suffered from vivid nightmares, and thoughts of violence while on serzone?? Im on seroquel, depakote, and serzone(2 weeks on serzone).Any comments appreciated.

Get to your doctor RIGHT AWAY. This is not good….and you shouldn’t be feeling that way. I understand what you are saying….almost like "night terrors". From the PDR for depakote and seroquel, "nightmares" are BOTH listed, so it may be a ‘double-whammy’…making your nightmares even worse. Just make sure you *emphasize* this to your doctor or pdoc, as it is not only unhealthy, but leaves you feeling very uncomfortable and unrested during the day. There are a couple of different meds available out there to combat nightmares, and you may benefit by either a combo of them and your above meds, or a reduction in your above meds and a few of the other meds. Here is a list of conversation from "psychobabble", a board in which pdocs post:

I have found clonidine 0.1 mg nightly particularly useful for disturbing dreams. I am not aware of the mechanism involved. I have had excellent results with surprisingly low doses of imipramine in similar situations, and for the patient who does not abuse medications, sometimes a benzodiazepine like alprazolam or even diazepam in low doses is useful. Oxazepam combined with imipramine can also be a useful combination in many patients, particularly if oversedation is a problem. Venlafaxine will often lead to vivid dreaming. The period of time during which the increased dreaming happens is often limited to 60-90 days. After the dreams normalize, more than a few patients report that they miss having their "super dreams." While I have never prescribed it to control the vividness of dreaming, a number of patients who close to bedtime had taken cyproheptadine to overcome the sexual side-effects of venlafaxine or one of the SSRIs report that the cyproheptadine in addition to improving sex also reduced the vividness of dreams. I’ve often had good luck with trazodone for various sleep complaints with SSRIs, usually 25-200 mg HS. It probably augments, too, so I can’t be sure if it’s a separate effect or not. I frequently prescribe Tenex (guanfacine) 2 mg HS to my PTSD patients with nightmares with excellent results most of the time. I was told by a sleep researcher that it is a powerful suppressor of REM sleep. Others should be able to contribute what helps. I have read of people using a couple of older triciyclics, such as imipramine. Also, a longer acting benzodiazepine MAY help…but that is up to your doctor to decide. Best wishes…I feel your pain in the horror of living each day with haunting memories from nightmares. They often ruin the whole following day for me, just because they seem so "real". YMMV, IMHO, etc… James

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