Question:
baby. sarah. — but my faith in love is still devout
Response:
baby. sarah.
Don’t even go there…it’s very dangerous territory, and you really don’t know what you are getting. Please don’t go there. Darren.
Response:
baby.
Also: Untoward neuropsychiatric effects Reports of adverse neuropsychiatric manifestations associated with MDMA use have included acute (within 24 hours of drug ingestion), subacute (greater than 24 hours and less than one month) and chronic (greater than one month) syndromes. In addition to the adverse effects described in the four studies previously mentioned (Downing, 1986; Greer & Tolbert, 1986; Peroutka et al., 1988, Liester et al. 1992), reported acute adverse effects of MDMA have included flashbacks, anxiety, insomnia (Greer & Strassman, 1985), panic attacks (Whitaker Azmitia & Aronson, 1989; McCann & Ricaurte, 1991) and psychosis (Creighton, Black & Hyde, 1991). Sub-acute adverse effects which have been reported following MDMA use have included drowsiness, depression, anxiety and irritability (Peroutka et al., 1988). Chronic neuropsychiatric difficulties seen following MDMA use include panic disorder (Pallanti & Mazzi, 1992; McCann & Ricaurte, 1992), psychosis (McGuire & Fahy, 1991; Creighton, Schifano, 199 1), flashbacks Black & Hyde, 199 1 3(Creighton et al., 1991), major depressive disorder (McCann et al., 1991; Benazzi & Mazzoli, 1991) and memory disturbance (McCann et al., 1991). The observation that only certain individuals develop neuropsychiatric disturbances following MDMA use suggests that certain predisposing psychiatric factors (or high dose regimens) may make some individuals more vulnerable to these untoward effects. Possible neurotoxic effects The neurotoxic dose of MDMA in non-human primates approaches the dose of MDMA typically taken by recreational MDMA users (Ricaurte & McCann, 1992). This raises the concern that human MDMA users might also incur MDMA-induced serotonin damage. Since there are no currently available methods for directly evaluating the status of serotonin neurones in living humans, studies of N4DMA’s neurotoxic potential in humans rely on indirect methods, including measurements of 5-HIAA in cerebrospinal fluid (CSF), and neuroendocrine challenge techniques. To date,, there have been two published studies which have used lumbar CSF 5-HIAA measurements to screen for possible MDMA-induced neurotoxicity in humans. One of these reported reductions in CSF 5-HIAA (Ricaurte et al., 1990), while the other did not (Peroutka, Pascoe & Faull, 1987). A third study, which used a neurcendocrine challenge test with L-tryptophan as a probe for serotonergic function suggested that MDMA users may have altered serotonindependent neuroendocrine function (Price eo al., 1988). None of these studies were conducted in controlled settings, so meaningful interpretation of these conflicting findings is problematic. Ongoing controlled studies evaluating MDMA users who have taken significant amounts of the drug in the past should help to clarify whether MDMA users, like MDMA-treated animals, incur damage to serotonin systems in the central nervous system. Darren.
Response:
Don’t even go there…it’s very dangerous territory, and you really don’t know what you are getting. Please don’t go there.
well i don’t want to act like i know stuff i mean i guess it’s too late to say ‘don’t go there’ although i haven’t gone to a rave in ages but MDMA-related deaths are extremely rare as compared to other hard drugs yes you risk things like hyperventilation and dehydration or i mean if you mix it with other stuff or you get some bad crap like MDA or whatever’s going around but really, the occasional use is really not dangerous and i’ve never met a person that had a negative experience yes, your brain gets fried when you eat x like candy but that’s not me all those medical terms you list are very impressive but very rare (well i think, anyway, but what do i know) besides i was just thinking and i was happy when i did it which is more than i can say for myself now sorry oxycodone please sarah. — but my faith in love is still devout
Response:
baby.
…and… MDMA has a range of effects that can lead to acute toxic reactions, including hyperthermia, raised blood pressure, raised heart rate, cardiac arrhythmias and coagulopathy.3 Hypertension may lead in turn to stroke, and hyperthermia to rhabdomyolysis, dehydration and renal failure. These effects appear to be caused by the action of MDMA on serotonergic and dopaminergic systems, resulting in increased release of neurotransmitters.4 This may explain the overlap of signs and symptoms of MDMA toxicity with those of the serotonin syndrome.5 Chronic toxicity has also been reported in animal models, with lesions of serotonergic neurons in the central nervous system after a few doses of MDMA. In primates, recovery of such lesions is slow and possibly incomplete.6 It is not known whether such toxicity occurs in humans. Some of the metabolites of MDMA (e.g., methylenedioxyamphetamine and dihydroxymethamphetamine) may contribute to the toxicity of the drug.7,8 Darren.
Response:
methylphenidate HCl is sometimes used in cases of refractory depression…(and it’s legal)
why would i bother with ritalin? if i wanted (and could get) prescription meds i’d just get percocet cos i love it or even better, oxycontin god GIVE me some of that sorry i know i’m coming across as a stupid druggy teenager not much i can do about that drinking just makes it worse. don’t smoke anymore (ha ha) so i don’t know i’m sad i can suck it up sarah. — but my faith in love is still devout
Response:
– Hide quoted text — Show quoted text – Well, sarah, whenever I see the words MDMA or Ecstasy, I get very concerned. I am not judging you at all. I am simply trying to make sure that you don’t get too far into the X scene, because it could be very dangerous. i know. and thank you for yr concern i guess i could ‘get into it’ if i wanted but people who really fry their brains really buy into the whole PLUR scene (well maybe not anymore) and i just couldn’t i need drugs i can do on my own i dunno i’m just looking for an easy out again easy way to feel better. i don’t care. give me whatever you have
methylphenidate HCl is sometimes used in cases of refractory depression…(and it’s legal) Darren.
Response:
Well, sarah, whenever I see the words MDMA or Ecstasy, I get very concerned. I am not judging you at all. I am simply trying to make sure that you don’t get too far into the X scene, because it could be very dangerous.
i know. and thank you for yr concern i guess i could ‘get into it’ if i wanted but people who really fry their brains really buy into the whole PLUR scene (well maybe not anymore) and i just couldn’t i need drugs i can do on my own i dunno i’m just looking for an easy out again easy way to feel better. i don’t care. give me whatever you have sarah. — but my faith in love is still devout
Response:
Well, it sounded originally like you wanted something to pick you up from depression, hence my reason for suggesting methylphenidate. Why then, would you be seeking CNS depressants if you are already depressed?
i don’t know i guess codeine is a downer or whatever so i guess that wouldn’t make sense but it’s not like i want to feel happy and feel a rush i guess it’s more the feeling of comfort and safety and warmth (jesus it just makes me teary-eyed just thinking about it, that’s when you know you’re bad) i mean i don’t know i tried ecstasy and it made me very very happy but i don’t long for that i want that feeling like you’re floating in the womb and you’re safe and someone has their arms lovingly around you i mean i don’t necessarily feel happy but i feel too comfortable, physically, to feel sad that’s all i know i don’t make sense sorry sarah. — but my faith in love is still devout
Response:
– Hide quoted text — Show quoted text – Don’t even go there…it’s very dangerous territory, and you really don’t know what you are getting. Please don’t go there. well i don’t want to act like i know stuff i mean i guess it’s too late to say ‘don’t go there’ although i haven’t gone to a rave in ages but MDMA-related deaths are extremely rare as compared to other hard drugs yes you risk things like hyperventilation and dehydration or i mean if you mix it with other stuff or you get some bad crap like MDA or whatever’s going around but really, the occasional use is really not dangerous and i’ve never met a person that had a negative experience yes, your brain gets fried when you eat x like candy but that’s not me all those medical terms you list are very impressive but very rare (well i think, anyway, but what do i know) besides i was just thinking and i was happy when i did it which is more than i can say for myself now sorry
Well, sarah, whenever I see the words MDMA or Ecstasy, I get very concerned. I am not judging you at all. I am simply trying to make sure that you don’t get too far into the X scene, because it could be very dangerous. Darren.
Response:
– Hide quoted text — Show quoted text – methylphenidate HCl is sometimes used in cases of refractory depression…(and it’s legal) why would i bother with ritalin? if i wanted (and could get) prescription meds i’d just get percocet cos i love it or even better, oxycontin god GIVE me some of that sorry i know i’m coming across as a stupid druggy teenager not much i can do about that drinking just makes it worse. don’t smoke anymore (ha ha) so i don’t know i’m sad i can suck it up
Well, it sounded originally like you wanted something to pick you up from depression, hence my reason for suggesting methylphenidate. Why then, would you be seeking CNS depressants if you are already depressed? Darren.
Response:
– Hide quoted text — Show quoted text – Well, sarah, whenever I see the words MDMA or Ecstasy, I get very concerned. I am not judging you at all. I am simply trying to make sure that you don’t get too far into the X scene, because it could be very dangerous. i know. and thank you for yr concern i guess i could ‘get into it’ if i wanted but people who really fry their brains really buy into the whole PLUR scene (well maybe not anymore) and i just couldn’t i need drugs i can do on my own i dunno i’m just looking for an easy out again easy way to feel better. i don’t care. give me whatever you have sarah. — but my faith in love is still devout
It is very sad to see you destroy yourself. Please, seek help from a mental health professional. Drug addiction (and depression) can be treated. Don’t throw away your life. Matt
Response:
– Hide quoted text — Show quoted text -Well, it sounded originally like you wanted something to pick you up from depression, hence my reason for suggesting methylphenidate. Why then, would you be seeking CNS depressants if you are already depressed? i don’t know i guess codeine is a downer or whatever so i guess that wouldn’t make sense but it’s not like i want to feel happy and feel a rush i guess it’s more the feeling of comfort and safety and warmth (jesus it just makes me teary-eyed just thinking about it, that’s when you know you’re bad) i mean i don’t know i tried ecstasy and it made me very very happy but i don’t long for that i want that feeling like you’re floating in the womb and you’re safe and someone has their arms lovingly around you i mean i don’t necessarily feel happy but i feel too comfortable, physically, to feel sad that’s all i know i don’t make sense sorry sarah. — but my faith in love is still devout
Has anyone ever told you that you have a addictive personality? Have you ever been hung up on booze? Heroin? Yes these are blunt sentences but I have the feelings you have and I leave them alone because they always get me into trouble. Please check into what makes you tick. toad
Response:
you don’t have to be pissed off at me i haven’t been to one in ages like i said you don’t need to get mad i didn’t say anything against you i mean maybe i’m a stupid teenager but that’s not a personal insult directed at you (i hope) sorry
Here I am poking in w/my 2 cents….. the comment didn’t seem like anything personal that you should be sorry for. It sounds like concern to me- I mean, imagine being the one trying to save the life of a young kid…..knowing that they’re teetering on the brink of death over something so unnecessary.
Response:
you don’t have to be pissed off at me i haven’t been to one in ages like i said you don’t need to get mad i didn’t say anything against you i mean maybe i’m a stupid teenager but that’s not a personal insult directed at you (i hope) sorry
I’m not mad at you. I’m just saying that it doesn’t take repeated use for X to fry your brain. I don’t think you’re just a stupid teenager (and, I hope you don’t, either). Being a teenager is enough of a hell as it is. I just hope you don’t do anything that leaves you screwed up with brain damage. No need to aplologize. Sorry if I upset you. Sasha What lies behind us and what lies before us are tiny matters compared to what lies within us. (Anonymous)
Response:
– Hide quoted text — Show quoted text – Well, it sounded originally like you wanted something to pick you up from depression, hence my reason for suggesting methylphenidate. Why then, would you be seeking CNS depressants if you are already depressed? i don’t know i guess codeine is a downer or whatever so i guess that wouldn’t make sense but it’s not like i want to feel happy and feel a rush i guess it’s more the feeling of comfort and safety and warmth (jesus it just makes me teary-eyed just thinking about it, that’s when you know you’re bad) i mean i don’t know i tried ecstasy and it made me very very happy but i don’t long for that i want that feeling like you’re floating in the womb and you’re safe and someone has their arms lovingly around you i mean i don’t necessarily feel happy but i feel too comfortable, physically, to feel sad that’s all i know i don’t make sense sorry
Hey, no need to apologise. I have been in deep depression myself, so having problems being logical with thoughts is part of my experience too. Darren.
Response:
i’ve had to perform cpr before. if i ever have to do it on someone who has put him/herself in a stupid and dangerous situation — i’ll be extremely pissed off.
you don’t have to be pissed off at me i haven’t been to one in ages like i said you don’t need to get mad i didn’t say anything against you i mean maybe i’m a stupid teenager but that’s not a personal insult directed at you (i hope) sorry sarah. — but my faith in love is still devout
Response:
yes, your brain gets fried when you eat x like candy
your brain gets fried when your body temp. goes up to very dangerous levels. you don’t have to eat it like candy. or even more than once. i’ve had to perform cpr before. if i ever have to do it on someone who has put him/herself in a stupid and dangerous situation — i’ll be extremely pissed off. What lies behind us and what lies before us are tiny matters compared to what lies within us. (Anonymous)
Response:
I guess my question for you is this, do you know what the answer is for you that doesn’t include mind altering substances?
i’m hoping, betting a lot on assuming, that it’s a good healthy relationship which i seem to be getting into and even still despite all that i mean…people can’t change your brain chemicals i mean, people don’t feel like drugs so, i guess nothing will take their place but yeah, i don’t know Is fear playing a part in this?
fear has been a part of my life since as far back as i can remember so it’s a safe bet to assume that’s involved to some degree i’m afraid that love won’t be enough and i’ll be crushed by this and get back on something even worse than painkillers can’t predict my actions anymore gave up on that a long time ago i am afraid of the nights now because i have nothing left, used up every pill and every drop, afraid of what i’d do to get more (but i won’t do it, no stealing from people’s medicine cabinets don’t worry just the idea that i could and would but i won’t) I will shut up now,
don’t do that. sarah. — but my faith in love is still devout
Response:
– Hide quoted text — Show quoted text -Has anyone ever told you that you have a addictive personality? as in possessing the ability to become easily addicted to something? no, but i figured it out myself Have you ever been hung up on booze? yes Heroin? tried it once. not going to go there Yes these are blunt sentences but I have the feelings you have and I leave them alone because they always get me into trouble. Please check into what makes you tick. i bet you could probably figure that out sarah. — but my faith in love is still devout
Ok we are both on the same page so to speak. I have been taking Atavan for 5 years. Not to get high but I think I swapped alcohol for them. Now I am trying to stop these but I do not get high on them. None the less when I don’t take one for bedtime I can’t sleep. I guess my question for you is this, do you know what the answer is for you that doesn’t include mind altering substances? Is fear playing a part in this? I will shut up now, toad
Response:
Has anyone ever told you that you have a addictive personality?
as in possessing the ability to become easily addicted to something? no, but i figured it out myself Have you ever been hung up on booze?
yes Heroin?
tried it once. not going to go there Yes these are blunt sentences but I have the feelings you have and I leave them alone because they always get me into trouble. Please check into what makes you tick.
i bet you could probably figure that out sarah. — but my faith in love is still devout
Response:
– Hide quoted text — Show quoted text -I guess my question for you is this, do you know what the answer is for you that doesn’t include mind altering substances? i’m hoping, betting a lot on assuming, that it’s a good healthy relationship which i seem to be getting into and even still despite all that i mean…people can’t change your brain chemicals i mean, people don’t feel like drugs so, i guess nothing will take their place but yeah, i don’t know Is fear playing a part in this? fear has been a part of my life since as far back as i can remember so it’s a safe bet to assume that’s involved to some degree i’m afraid that love won’t be enough and i’ll be crushed by this and get back on something even worse than painkillers can’t predict my actions anymore gave up on that a long time ago i am afraid of the nights now because i have nothing left, used up every pill and every drop, afraid of what i’d do to get more (but i won’t do it, no stealing from people’s medicine cabinets don’t worry just the idea that i could and would but i won’t) I will shut up now, don’t do that. sarah. — but my faith in love is still devout
I sorry I don’t have answers to fix you or me but I do read what you write and wish I could fix everybody here. I do know that addiction becomes you like in invasion of the body snatchers. Have you ever listened to "life by to drop" Stevie Ray Vaughn? It holds a lot of meaning for me. My best, toad
Response:
Here I am poking in w/my 2 cents….. the comment didn’t seem like anything personal that you should be sorry for. It sounds like concern to me- I mean, imagine being the one trying to save the life of a young kid…..knowing that they’re teetering on the brink of death over something so unnecessary.
You hit the nail on the head. That’s exactly what I meant. (It wasn’t personal.) What lies behind us and what lies before us are tiny matters compared to what lies within us. (Anonymous)
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